A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

DPA44

tert-Butyloxycarbonyl-Proline-α,β‐dehydrophenylalanine-Glycine-α,β‐dehydrophenylalanine-Alanine-Methyl ester

Sequence: Boc-P-ΔF-G-ΔF-A-OMe

Core Sequence: P-ΔF-G-ΔF-A

R Value: 0.0685

Residue Involved: Proline | α,β‐dehydrophenylalanine | Glycine | α,β‐dehydrophenylalanine | Alanine

Conformation: Right-handed 3(10) helical

Reference

Mathur, P., Ramagopal, UA., Ramakumar, S., Jagannathan, NR., Chauhan, VS. (2005) Stabilization of Unusual Structures in Peptides Using a,b-Dehydrophenylalanine: Crystal and Solution Structures of Boc–Pro–DPhe–Val–DPhe–Ala–OMe and Boc–Pro–DPhe–Gly–DPhe–Ala–OMe

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Proline-α,β‐dehydrophenylalanine-Glycine-α,β‐dehydrophenylalanine-Alanine-Methyl ester
Sequence: Boc-P-ΔF-G-ΔF-A-OMe
Core Sequence: P-ΔF-G-ΔF-A
Sequence Length: 5
Molecular Weight (amu): 636.7
Molecular Formula: C33-H42-N5-O8
R Value: 0.0685
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Right-handed 3(10) helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Proline -83.4 116.9 Unmeasured
α,β‐dehydrophenylalanine -54.2 -24 Unmeasured
Glycine -66 -7.5
α,β‐dehydrophenylalanine -56.4 -24.1
Alanine -71.2 156.3