A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

DPA38

tert-Butyloxycarbonyl-Valine-α,β‐dehydrophenylalanine-α,β‐dehydrophenylalanine-α,β‐dehydrophenylalanine-Valine-Methyl ester

Sequence: Boc-V-ΔF-ΔF-ΔF-V-OMe

Core Sequence: V-ΔF-ΔF-ΔF-V

R Value: 0.097

Residue Involved: Valine | α,β‐dehydrophenylalanine | α,β‐dehydrophenylalanine | α,β‐dehydrophenylalanine | Valine

Conformation: Left-handed 3(10) helical

Reference

Jain, R., Rajashankar, K., Ramakumar, S. and Chauhan, V. (1997). First Observation of Left-Handed Helical Conformation in a Dehydro Peptide Containing Twol-Val Residues. Crystal and Solution Structure of Boc-l-Val-ΔPhe-ΔPhe-ΔPhe-l-Val-OMe†,⊥. Journal of the American Chemical Society, 119(14), pp.3205-3211.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Valine-α,β‐dehydrophenylalanine-α,β‐dehydrophenylalanine-α,β‐dehydrophenylalanine-Valine-Methyl ester
Sequence: Boc-V-ΔF-ΔF-ΔF-V-OMe
Core Sequence: V-ΔF-ΔF-ΔF-V
Sequence Length: 5
Molecular Weight (amu): 765.915
Molecular Formula: C43H51N5O8
R Value: 0.097
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Left-handed 3(10) helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Valine -56 131.2 179.8
α,β‐dehydrophenylalanine 56 18.4 -168.3
α,β‐dehydrophenylalanine 58.1 13 -171.3
α,β‐dehydrophenylalanine 78.2 4.5 178
Valine -122.5 120.3