A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

DPA35

tert-Butyloxycarbonyl-Valine-α,β‐dehydrophenylalanine-Leucine-Phenylalanine-Alanine-α,β‐dehydrophenylalanine-Leucine-Methyl ester

Sequence: Boc-V-ΔF-L-F-A-ΔF-L-OMe

Core Sequence: V-ΔF-L-F-A-ΔF-L

R Value: 0.061

Residue Involved: Valine | α,β‐dehydrophenylalanine | Leucine | Phenylalanine | Alanine | α,β‐dehydrophenylalanine | Leucine

Conformation: Schellman Motif -3(10) helix

Reference

Mal, T., Jain, R., Chauhan, V., Rajashankar, K. and Ramakumar, S. (1996). Schellman Motif in Dehydrooligopeptides: Crystal and Molecular Structure of Boc-Val-ΔPhe-Leu-Phe-Ala-ΔPhe-Leu-OMe. Angewandte Chemie International Edition in English, 35(7), pp.765-768.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Valine-α,β‐dehydrophenylalanine-Leucine-Phenylalanine-Alanine-α,β‐dehydrophenylalanine-Leucine-Methyl ester
Sequence: Boc-V-ΔF-L-F-A-ΔF-L-OMe
Core Sequence: V-ΔF-L-F-A-ΔF-L
Sequence Length: 7
Molecular Weight (amu): 966.198
Molecular Formula: C53H71N7O10
R Value: 0.061
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Schellman Motif -3(10) helix
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Valine -52.8 -40.1 -179.2
α,β‐dehydrophenylalanine -54.2 -31.4 176.2
Leucine -75.2 -40.3 172.7
Phenylalanine -62.7 -22.7 -179.7
Alanine -83.7 -9.5 -178.8
α,β‐dehydrophenylalanine 95.7 -3.6 -177.6
Leucine -62.6 -39.3 178.3