A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

DPA34

tert-Butyloxycarbonyl-Valine-α,β‐dehydrophenylalanine-Leucine-Alanine-α,β‐dehydrophenylalanine-Alanine-Methyl ester

Sequence: Boc-V-ΔF-L-A-ΔF-A-OMe

Core Sequence: V-ΔF-L-A-ΔF-A

R Value: 0.046

Residue Involved: Valine | α,β‐dehydrophenylalanine | Leucine | Alanine | α,β‐dehydrophenylalanine | Alanine

Conformation: Right-handed 3(10) helical

Reference

Padyana, A., Ramakumar, S., Mathur, P., Jagannathan, N. and Chauhan, V. (2003). Role of a two-residue spacer in an ?,?-didehydrophenylalanine containing hexapeptide: crystal and solution structure of Boc-Val-?Phe-Leu-Ala-?Phe-Ala-OMe. Journal of Peptide Science, 9(1), pp.54-63.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Valine-α,β‐dehydrophenylalanine-Leucine-Alanine-α,β‐dehydrophenylalanine-Alanine-Methyl ester
Sequence: Boc-V-ΔF-L-A-ΔF-A-OMe
Core Sequence: V-ΔF-L-A-ΔF-A
Sequence Length: 6
Molecular Weight (amu): 774.93
Molecular Formula: C41-H56-N6O9
R Value: 0.046
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Right-handed 3(10) helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Valine -61.4 -39.6 -168.3
α,β‐dehydrophenylalanine -72.0 -11.4 172.5
Leucine -55.8 -36.7 169.8
Alanine -68.5 -17.5 179.7
α,β‐dehydrophenylalanine -81.8 -9.0 178.6
Alanine -67.2 149.5 -179.7