A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

DPA30

tert-Butyloxycarbonyl-Valine-α,β‐dehydrophenylalanine- α,β‐dehydrophenylalanine-Isoleucine-Methyl ester

Sequence: Boc-V-ΔF- ΔF-I-OMe

Core Sequence: V-ΔF-ΔF-I

R Value: 0.073

Residue Involved: Valine | α,β‐dehydrophenylalanine | α,β‐dehydrophenylalanine | Isoleucine

Conformation: Right-handed 3(10) helical

Reference

Bhatia, S., Kumar, P., Kaur, P. and Singh, T. (2008). Design of peptides withα,β-dehydro-residues: synthesis, and crystal and molecular structure of a310-helical tetrapeptide Boc-l-Val-ΔPhe-ΔPhe-l-Ile-OCH3. The Journal of Peptide Research, 54(3), pp.249-255.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Valine-α,β‐dehydrophenylalanine- α,β‐dehydrophenylalanine-Isoleucine-Methyl ester
Sequence: Boc-V-ΔF- ΔF-I-OMe
Core Sequence: V-ΔF-ΔF-I
Sequence Length: 4
Molecular Weight (amu): 634.771
Molecular Formula: C35-H46-N4-07
R Value: 0.073
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Right-handed 3(10) helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Valine -56.0 -38.0 177.7
α,β‐dehydrophenylalanine -53.8 -23.6 -179.7
α,β‐dehydrophenylalanine -82.9 -10.6 -169.4
Isoleucine -158.0 28.7 Unmeasured