A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

DPA27

tert-Butyloxycarbonyl-Proline-α,β‐dehydrophenylalanine-Alanine- α,β‐dehydrophenylalanine-Alanine-Methyl ester

Sequence: Boc-P-ΔF-A- ΔF-A-OMe

Core Sequence: P-ΔF-A-ΔF

R Value: 0.056

Residue Involved: Proline | α,β‐dehydrophenylalanine | Alanine | α,β‐dehydrophenylalanine

Conformation: Type II β‐Bend

Reference

Rajashankar, K., Ramakumar, S., Mal, T. and Chauhan, V. (1994). Synthesis, Crystal and Molecular Structure of Boc-Pro-ΔPhe-Ala-ΔPhe- Ala-OMe; A Pentapeptide with a Novelβ-Bend Ribbon Structure. Angewandte Chemie International Edition in English, 33(9), pp.970-973.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Proline-α,β‐dehydrophenylalanine-Alanine- α,β‐dehydrophenylalanine-Alanine-Methyl ester
Sequence: Boc-P-ΔF-A- ΔF-A-OMe
Core Sequence: P-ΔF-A-ΔF
Sequence Length: 4
Molecular Weight (amu): 661.75
Molecular Formula: C35-H43-N5-O8
R Value: 0.056
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Type II β‐Bend
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Proline -64.4 -28.5 179.3
α,β‐dehydrophenylalanine -80.6 -7.3 -173.4
Alanine -65.8 129.9 178.8
α,β‐dehydrophenylalanine 77.2 3.3 169.8