A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

DPA26

tert-Butyloxycarbonyl-Leucine-α,β‐dehydrophenylalanine-α,β‐dehydrophenylalanine-Alanine-Phenylalanine-Methylamide

Sequence: Boc-L-ΔF-ΔF-A-F-NHMe

Core Sequence: L-ΔF-ΔF-A-F

R Value: 0.053

Residue Involved: Leucine | α,β‐dehydrophenylalanine | α,β‐dehydrophenylalanine | Alanine | Phenylalanine

Conformation: Right-handed 3(10) helical

Reference

Rajashankar, K., Ramakumar, S., Jain, R. and Chauhan, V. (1997). Role of two consecutive α,β-dehydrophenylalanines in peptide structure: Crystal and molecular structure of Boc-Leu-ΔPhe-ΔPhe-Ala-Phe-NHMe. Biopolymers, 42(3), pp.373-382.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Leucine-α,β‐dehydrophenylalanine-α,β‐dehydrophenylalanine-Alanine-Phenylalanine-Methylamide
Sequence: Boc-L-ΔF-ΔF-A-F-NHMe
Core Sequence: L-ΔF-ΔF-A-F
Sequence Length: 5
Molecular Weight (amu): 752.9
Molecular Formula: C42-H51-N5O7
R Value: 0.053
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methylamide
Conformation: Right-handed 3(10) helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Leucine -57.6 -45.9 179.3
α,β‐dehydrophenylalanine 52.8 -29.8 178.6
α,β‐dehydrophenylalanine -59.6 -22.8 -178.6
Alanine -78.6 -22.9 -176.2
Phenylalanine -92.5 -6.6 -175.3