A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB9

tert-Butyloxycarbonyl-Valine-Alanine-Phenylalanine-Alpha amino iso butyric acid-Valine-Alanine-Phenylalanine-Alpha amino iso butyric acid-Valine-Alanine-Phenylalanine-Alpha amino iso butyric acid-Methyl ester

Sequence: Boc-V-A-F-Aib-V-A-F-Aib-V-A-F-Aib-OMe

Core Sequence: V-A-F-Aib-V-A-F-Aib-V-A-F-Aib

R Value: Unknown

Residue Involved: Valine| Alanine| Phenylalanine| Alpha amino iso butyric acid | Valine| Alanine| Phenylalanine| Alpha amino iso butyric acid | Valine| Alanine| Phenylalanine| Alpha amino iso butyric acid

Conformation: Helical

Reference

Roy, R., Karle, I., Raghothama, S. and Balaram, P. (2004). , hybrid peptides: A polypeptide helix with a central segment containing two consecutive -amino acid residues. Proceedings of the National Academy of Sciences, 101(47), pp.16478-16482.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Valine-Alanine-Phenylalanine-Alpha amino iso butyric acid-Valine-Alanine-Phenylalanine-Alpha amino iso butyric acid-Valine-Alanine-Phenylalanine-Alpha amino iso butyric acid-Methyl ester
Sequence: Boc-V-A-F-Aib-V-A-F-Aib-V-A-F-Aib-OMe
Core Sequence: V-A-F-Aib-V-A-F-Aib-V-A-F-Aib
Sequence Length: 12
Molecular Weight (amu): 1295.6+39
Molecular Formula: C68-H101-N11-O14-C2-H3-N
R Value: Unknown
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Valine 43 173 177
Alanine -73 42 -165
Phenylalanine -90 -35 178
Alpha amino iso butyric acid -60 -28 173
Valine -126 -47 172
Alanine -88 -124 -169
Phenylalanine -55 -118 -165
Alpha amino iso butyric acid -63 -49 -178
Valine -60 -42 -179
Alanine -79 -37 177
Phenylalanine 42 -58 -171
Alpha amino iso butyric acid 49 178