A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB43

tert-Butyloxycarbonyl-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester

Sequence: Boc-Aib-V-A-L-Aib-V-A-L-Aib-OMe

Core Sequence: Aib-V-A-L-Aib-V-A-L-Aib

R Value: Unknown

Residue Involved: Alpha amino iso butyric acid | Valine| Alanine| Leucine| Alpha amino iso butyric acid | Valine| Alanine| Leucine| Alpha amino iso butyric acid

Conformation: 3(10) helical

Reference

KARLE, I., FLIPPEN-ANDERSON, J., UMA, K. and BALARAM, P. (2009). Aggregation studies in crystals of apolar helical peptides: Boc-Aib-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe. International Journal of Peptide and Protein Research, 32(6), pp.536-543.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester
Sequence: Boc-Aib-V-A-L-Aib-V-A-L-Aib-OMe
Core Sequence: Aib-V-A-L-Aib-V-A-L-Aib
Sequence Length: 9
Molecular Weight (amu): 954.23+59.84
Molecular Formula: C46-H83-N9-O12*1.5H20*0.67CH3-OH
R Value: Unknown
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: 3(10) helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Alpha amino iso butyric acid -55.9 -34.4 -177.7
Valine -58.2 -37.3 179.9
Alanine -64.6 -36.9 177.6
Leucine -72.4 -40.5 177.5
Alpha amino iso butyric acid -50.2 -44.7 -178.7
Valine -71.9 -41.9 179.6
Alanine -58.9 -32.7 -170.7
Leucine -89.1 -8.1 178.3
Alpha amino iso butyric acid -53.6 -39.3