A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB42

tert-Butyloxycarbonyl-Alanine-Leucine-Alpha amino iso butyric acid-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester

Sequence: Boc-A-L-Aib-A-L-Aib-OMe

Core Sequence: A-L-Aib-A-L-Aib

R Value: 0.063

Residue Involved: Alanine| Leucine| Alpha amino iso butyric acid | Alanine| Leucine| Alpha amino iso butyric acid

Conformation: Helical

Reference

Karle, I., Flippen-Anderson, J., Uma, K. and Balaram, P. (1989). Solvated helical backbones: X-ray diffraction study of Boc-Ala-Leu-Aib-Ala-Leu-Aib-OMe · H2O. Biopolymers, 28(3), pp.773-781.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Alanine-Leucine-Alpha amino iso butyric acid-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester
Sequence: Boc-A-L-Aib-A-L-Aib-OMe
Core Sequence: A-L-Aib-A-L-Aib
Sequence Length: 6
Molecular Weight (amu): 684.88
Molecular Formula: C32-H58-N6-O9 . H20
R Value: 0.063
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Alanine -74.4 -16.2 178.8
Leucine -90.9 17.9 -173.9
Alpha amino iso butyric acid -51.1 -41.4 -177.1
Alanine -60.9 -20.7 -175
Leucine -95.3 -1.8 -166.6
Alpha amino iso butyric acid -53.1 -53.9 -171.4