A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB40

tert-Butyloxycarbonyl-Alpha amino iso butyric acid-Alanine-Alpha amino iso butyric acid-Alanine-Leucine-Alanine-Leucine-Alpha amino iso butyric acid-Leucine-Alpha amino iso butyric acid-Methyl ester

Sequence: Boc-Aib-A-Aib-A-L-A-L-Aib-L-Aib-OMe

Core Sequence: Aib-A-Aib-A-L-A-L-Aib-L-Aib

R Value: 0.083

Residue Involved: Alpha amino iso butyric acid | Alanine| Alpha amino iso butyric acid | Alanine| Leucine| Alanine| Leucine| Alpha amino iso butyric acid | Leucine| Alpha amino iso butyric acid

Conformation: Alpha helical

Reference

Karle, I., Flippen-Anderson, J., Uma, K. and Balaram, P. (1990). Synthetic peptide helices in crystals: Structure and antiparallel and skewed packing motifs for ?-helices in two isomeric decapeptides. Biopolymers, 30(7-8), pp.719-731.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Alpha amino iso butyric acid-Alanine-Alpha amino iso butyric acid-Alanine-Leucine-Alanine-Leucine-Alpha amino iso butyric acid-Leucine-Alpha amino iso butyric acid-Methyl ester
Sequence: Boc-Aib-A-Aib-A-L-A-L-Aib-L-Aib-OMe
Core Sequence: Aib-A-Aib-A-L-A-L-Aib-L-Aib
Sequence Length: 10
Molecular Weight (amu): 1025.2+9
Molecular Formula: C49-H88-N10-O13 * 1/2H20
R Value: 0.083
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Alpha helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Alpha amino iso butyric acid -59 -59 -169
Alanine -63 -44 178
Alpha amino iso butyric acid -57 -52 -174
Alanine -66 -37 177
Leucine -63 -43 179
Alanine -67 -42 179
Leucine -62 -42 -178
Alpha amino iso butyric acid -58 -36 -176
Leucine -89 -27 171
Alpha amino iso butyric acid 53 49 173