A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB39

tert-Butyloxycarbonyl-Alpha amino iso butyric acid-Alanine-Leucine-Alanine-Alpha amino iso butyric acid-Amino-iso-butyric-Leucine-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester

Sequence: Boc-Aib-A-L-A-Aib-Aib-L-A-L-Aib-OMe

Core Sequence: Aib-A-L-A-Aib-Aib-L-A-L-Aib

R Value: 0.057

Residue Involved: Alpha amino iso butyric acid | Alanine| Leucine| Alanine| Alpha amino iso butyric acid | Alpha amino iso butyric acid | Leucine| Alanine| Leucine| Alpha amino iso butyric acid

Conformation: Alpha helical

Reference

Karle, I., Flippen-Anderson, J., Uma, K. and Balaram, P. (1990). Synthetic peptide helices in crystals: Structure and antiparallel and skewed packing motifs for ?-helices in two isomeric decapeptides. Biopolymers, 30(7-8), pp.719-731.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Alpha amino iso butyric acid-Alanine-Leucine-Alanine-Alpha amino iso butyric acid-Amino-iso-butyric-Leucine-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester
Sequence: Boc-Aib-A-L-A-Aib-Aib-L-A-L-Aib-OMe
Core Sequence: Aib-A-L-A-Aib-Aib-L-A-L-Aib
Sequence Length: 10
Molecular Weight (amu): 1025.2
Molecular Formula: C49-H88-N10-O13
R Value: 0.057
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Alpha helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Alpha amino iso butyric acid -58 -48 -173
Alanine -65 -35 -179
Leucine -71 -38 178
Alanine -61 -47 179
Alpha amino iso butyric acid -57 -54 -175
Alpha amino iso butyric acid -56 -51 -169
Leucine -75 -36 180
Alanine -71 -23 179
Leucine -91 -28 -167
Alpha amino iso butyric acid 49 40 180