A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB38

tert-Butyloxycarbonyl-Tryptophan-Isoleucine-Alanine-Alpha amino iso butyric acid-Isoleucine-Valine-Alpha amino iso butyric acid-Leucine-Alpha amino iso butyric acid-Proline-Methyl ester

Sequence: Boc-W-I-A-Aib-I-V-Aib-L-Aib-P-OMe

Core Sequence: W-I-A-Aib-I-V-Aib-L-Aib-P

R Value: 0.055

Residue Involved: Tryptophan| Isoleucine| Alanine| Alpha amino iso butyric acid | Isoleucine| Valine| Alpha amino iso butyric acid | Leucine| Alpha amino iso butyric acid | Proline

Conformation: Helical

Reference

KARLE, I., FLIPPEN-ANDERSON, J., SUKUMAR, M. and BALARAM, P. (2009). Parallel and antiparallel aggregation of α-helices. International Journal of Peptide and Protein Research, 35(6), pp.518-526.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Tryptophan-Isoleucine-Alanine-Alpha amino iso butyric acid-Isoleucine-Valine-Alpha amino iso butyric acid-Leucine-Alpha amino iso butyric acid-Proline-Methyl ester
Sequence: Boc-W-I-A-Aib-I-V-Aib-L-Aib-P-OMe
Core Sequence: W-I-A-Aib-I-V-Aib-L-Aib-P
Sequence Length: 10
Molecular Weight (amu): 1180.6+60.1
Molecular Formula: C60-H97-O13-C3-H2-OH
R Value: 0.055
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Tryptophan -57.5 -31.5 -177.1
Isoleucine -61.4 -30.1 177.9
Alanine -60.9 -48.3 177.8
Alpha amino iso butyric acid -54.8 -47.4 -175
Isoleucine -66.3 -38 177.8
Valine -60.9 -44.5 179.1
Alpha amino iso butyric acid -58.8 -35.9 -179.8
Leucine -72.9 -27.9 168.4
Alpha amino iso butyric acid 50 50.8 -179.5
Proline -61.9 144 179.1