A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB36

tert-Butyloxycarbonyl-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Methyl ester

Sequence: Boc-V-A-L-Aib-V-A-L-OMe

Core Sequence: V-A-L-Aib-V-A-L

R Value: 0.0665

Residue Involved: Valine| Alanine| Leucine| Alpha amino iso butyric acid | Valine| Alanine| Leucine

Conformation: Helical

Reference

Karle, I., Flippen-Anderson, J., Uma, K. and Balaram, P. (1990). Apolar peptide models for conformational heterogeneity, hydration, and packing of polypeptide helices: Crystal structure of hepta- and octapeptides containing α-aminoisobutyric acid. Proteins: Structure, Function, and Genetics, 7(1), pp.62-73.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Methyl ester
Sequence: Boc-V-A-L-Aib-V-A-L-OMe
Core Sequence: V-A-L-Aib-V-A-L
Sequence Length: 7
Molecular Weight (amu): 783.0 + 9.0
Molecular Formula: C38-H69-N7-O10 -1/2H2O
R Value: 0.0665
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Valine -71 -41 -178
Alanine -61 -45 179
Leucine -71 -35 180
Alpha amino iso butyric acid -57 -35 -178
Valine -87 -87 173
Alanine -78 -41 -175
Leucine -127 10 176