A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB29

tert-Butyloxycarbonyl-Alanine-Leucine-Alpha amino iso butyric acid-Alanine-Leucine-Alpha amino iso butyric acid-Alanine-Leucine-Alpha amino iso butyric acid-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester

Sequence: Boc-A-L-Aib-A-L-Aib-A-L-Aib-A-L-Aib-OMe

Core Sequence: A-L-Aib-A-L-Aib-A-L-Aib-A-L-Aib

R Value: 0.109

Residue Involved: Alanine| Leucine| Alpha amino iso butyric acid | Alanine| Leucine| Alpha amino iso butyric acid | Alanine| Leucine| Alpha amino iso butyric acid | Alanine| Leucine| Alpha amino iso butyric acid

Conformation: Helical

Reference

DATTA, S., SHAMALA, N., BANERJEE, A. and BALARAM, P. (2009). Hydrogen bonding in peptide helices Analysis of two independent helices in the crystal structure of a peptide Boc-Val-Ala-Leu-Aib-Val-Ala-Phe-OMe. The Journal of Peptide Research, 49(6), pp.604-611.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Alanine-Leucine-Alpha amino iso butyric acid-Alanine-Leucine-Alpha amino iso butyric acid-Alanine-Leucine-Alpha amino iso butyric acid-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester
Sequence: Boc-A-L-Aib-A-L-Aib-A-L-Aib-A-L-Aib-OMe
Core Sequence: A-L-Aib-A-L-Aib-A-L-Aib-A-L-Aib
Sequence Length: 12
Molecular Weight (amu): 1209.55
Molecular Formula: C58-H104-N12-O15
R Value: 0.109
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Alanine -52 -30 178
Leucine -49 -45 175
Alpha amino iso butyric acid -60 -48 179
Alanine -68 -32 174
Leucine -69 -34 175
Alpha amino iso butyric acid -51 -56 -175
Alanine -66 -42 179
Leucine -60 -44 180
Alpha amino iso butyric acid -50 -48 -176
Alanine -64 -48 177
Leucine -62 -56 180
Alpha amino iso butyric acid 50 38 -175