A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB24

Acetyl-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester

Sequence: Ac-Aib-V-A-L-Aib-V-A-L-Aib-OMe

Core Sequence: Aib-V-A-L-Aib-V-A-L-Aib

R Value: 0.0796

Residue Involved: Alpha amino iso butyric acid | Valine| Alanine| Leucine| Alpha amino iso butyric acid | Valine| Alanine| Leucine| Alpha amino iso butyric acid

Conformation: 3(10) helical

Reference

Karle, I., Flippen‐Anderson, J., Uma, K. and Balaram, P. (1996). Effects of End Group and Aggregation on Helix Conformation: Crystal Structure of Ac-(Aib‐Val‐Ala‐Leu)2-Aib- OMe. Journal of Peptide Science, 2(2), pp.106-116.

Chemical Component Summary

Name of Peptide: Acetyl-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Methyl ester
Sequence: Ac-Aib-V-A-L-Aib-V-A-L-Aib-OMe
Core Sequence: Aib-V-A-L-Aib-V-A-L-Aib
Sequence Length: 9
Molecular Weight (amu): 896
Molecular Formula: C43-H77-N9-O11
R Value: 0.0796
N-Terminal Modification: Acetyl
C-Terminal Modification: Methyl ester
Conformation: 3(10) helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Alpha amino iso butyric acid -51 -42 -177
Valine -60 -39 180
Alanine -65 -37 178
Leucine -73 -34 175
Alpha amino iso butyric acid -51 -49 -175
Valine -73 -37 -178
Alanine -67 -31 -179
Leucine -94 -41 -174
Alpha amino iso butyric acid 49 49 171