A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB23

tert-Butyloxycarbonyl-Leucine-Alpha amino iso butyric acid-Valine-Glycine-Glycine-Leucine-Alpha amino iso butyric acid-Valine-Methyl ester

Sequence: Boc-L-Aib-V-G-G-L-Aib-V-OMe

Core Sequence: L-Aib-V-G-G-L-Aib-V

R Value: 0.077

Residue Involved: Leucine| Alpha amino iso butyric acid | Valine| Glycine| Glycine| Leucine| Alpha amino iso butyric acid | Valine

Conformation: Helical

Reference

Karle, I., Banerjee, A., Bhattacharjya, S. and Balaram, P. (1996). Solid state and solution conformations of a helical peptide with a central gly‐gly segment. Biopolymers, 38(4), pp.515-526.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Leucine-Alpha amino iso butyric acid-Valine-Glycine-Glycine-Leucine-Alpha amino iso butyric acid-Valine-Methyl ester
Sequence: Boc-L-Aib-V-G-G-L-Aib-V-OMe
Core Sequence: L-Aib-V-G-G-L-Aib-V
Sequence Length: 8
Molecular Weight (amu): 841.1 + 32
Molecular Formula: C40-H72-N8-011I + C-H3-0-H
R Value: 0.077
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Leucine -56 -35 -175
Alpha amino iso butyric acid -50 -40 -175
Valine -63 -28 175
Glycine -65 -23 176
Glycine -64 -24 180
Leucine -81 -16 176
Alpha amino iso butyric acid 53 49 169
Valine -51 -35 171g