A manually curated database of peptides containing Dehydro-Phenyl-Alanine and Amino-Iso-Butyric Acid
Protein Data Bank[PDB] Structured Data File [SDF]

AIB16

tert-Butyloxycarbonyl-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Methyl ester

Sequence: Boc-V-A-L-Aib-V-A-L-Aib-V-A-L-OMe

Core Sequence: V-A-L-Aib-V-A-L-Aib-V-A-L

R Value: 0.043

Residue Involved: Valine| Alanine| Leucine| Alpha amino iso butyric acid | Valine| Alanine| Leucine| Alpha amino iso butyric acid | Valine| Alanine| Leucine

Conformation: Alpha helical

Reference

Aravinda, S., Shamala, N., Das, C. and Balaram, P. (2002). Structural analysis of peptide helices containing centrally positioned lactic acid residues. Biopolymers, 64(5), pp.255-267.

Chemical Component Summary

Name of Peptide: tert-Butyloxycarbonyl-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Alpha amino iso butyric acid-Valine-Alanine-Leucine-Methyl ester
Sequence: Boc-V-A-L-Aib-V-A-L-Aib-V-A-L-OMe
Core Sequence: V-A-L-Aib-V-A-L-Aib-V-A-L
Sequence Length: 11
Molecular Weight (amu): 120.63
Molecular Formula: C56-H101- N11-O14 - 3H2-O
R Value: 0.043
N-Terminal Modification: tert-Butyloxycarbonyl
C-Terminal Modification: Methyl ester
Conformation: Alpha helical
Method: X - Ray Diffraction
Core Residue Involved Phi Psi Omega
Valine -63.2 -53.4 -173.8
Alanine -64.3 -43.1 -179.6
Leucine -68.2 -40.7 176.2
Alpha amino iso butyric acid -51.8 -51.5 -176.9
Valine -64.5 -46.6 -179.2
Alanine -55.5 -46.4 -179.1
Leucine -67.2 -47.9 -174.1
Alpha amino iso butyric acid -59.8 -34 -176
Valine -92 -42.7 -178.2
Alanine -71 -37.7 173.6
Leucine -80.3 -47.2 176.9